Scanning electron microscopy (SEM) images of C. lusitaniae on
filament-inducing media. Cells grown on V8 (pH = 7) media for 7
days at 37°C were processed for SEM, and imaged (see
Materials and Methods from Zhang et al., 2012). Scale bars for
upper panel (1000x) and lower panel (5000x) images represent 10
µm and 2 µm, respectively. WT
(ATCC42720), cnb1 mutant (YC198), and crz1 mutant (YC187). Image
made available by Zhang et al., 2012
Clavispora lusitaniae is a member of the Saccharomycotina sequenced by Butler et al., 2014. It can be a human pathogen, and has developed resistance to Amphotericin-B, a common anti-fungal to treat fungal infections (Krcmery and Barnes, 2002). C. lusitaniae belongs to the CUG clade, which substitute serine for leucine at CUG codons. C. lusitaniae was imported into mycocosm for comparative purposes.
Genome Reference(s)
Please cite the following publication(s) if you use the data from this genome in your research:
Butler G, Rasmussen MD, Lin MF, Santos MA, Sakthikumar S, Munro CA, Rheinbay E, Grabherr M, Forche A, Reedy JL, Agrafioti I, Arnaud MB, Bates S, Brown AJ, Brunke S, Costanzo MC, Fitzpatrick DA, de Groot PW, Harris D, Hoyer LL, Hube B, Klis FM, Kodira C, Lennard N, Logue ME, Martin R, Neiman AM, Nikolaou E, Quail MA, Quinn J, Santos MC, Schmitzberger FF, Sherlock G, Shah P, Silverstein KA, Skrzypek MS, Soll D, Staggs R, Stansfield I, Stumpf MP, Sudbery PE, Srikantha T, Zeng Q, Berman J, Berriman M, Heitman J, Gow NA, Lorenz MC, Birren BW, Kellis M, Cuomo CA
Evolution of pathogenicity and sexual reproduction in eight Candida genomes.
Nature. 2009 Jun 4;459(7247):657-62. doi: 10.1038/nature08064
Butler G, Rasmussen MD, Lin MF, Santos MA, Sakthikumar S, Munro CA, Rheinbay E, Grabherr M, Forche A, Reedy JL, Agrafioti I, Arnaud MB, Bates S, Brown AJ, Brunke S, Costanzo MC, Fitzpatrick DA, de Groot PW, Harris D, Hoyer LL, Hube B, Klis FM, Kodira C, Lennard N, Logue ME, Martin R, Neiman AM, Nikolaou E, Quail MA, Quinn J, Santos MC, Schmitzberger FF, Sherlock G, Shah P, Silverstein KA, Skrzypek MS, Soll D, Staggs R, Stansfield I, Stumpf MP, Sudbery PE, Srikantha T, Zeng Q, Berman J, Berriman M, Heitman J, Gow NA, Lorenz MC, Birren BW, Kellis M, Cuomo CA
Evolution of pathogenicity and sexual reproduction in eight Candida genomes.
Nature. 2009 Jun 4;459(7247):657-62. doi: 10.1038/nature08064
Additional references:
Krcmery, V., and A. J. Barnes. "Non-albicans
Candida spp. causing fungaemia: pathogenicity and antifungal
resistance." Journal of Hospital Infection 50.4 (2002):
243-260.
